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Filtered Search Results
Ambeed Dicyclohexyl 2 6 diisopropoxy
Dicyclohexyl(2',6'-diisopropoxy-[1,1'-biphenyl]-2-yl)phosphine, 787618-22-8, 97%
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Selleck Chemical LLC Resiquimod
Resiquimod (R-848 S28463) is an immune response modifier that acts as a potent TLR 7/TLR 8 agonist that induces the upregulation of cytokines such as TNF- IL-6 and IFN- Resiquimod reduces hepatitis C virus (HCV) infection Phase 2
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000568502 TRYPTOPHOL-200MG
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Medchemexpress LLC Chelerythrine chloride | 3895-92-9 | >98.0% | 5MG
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Chelerythrine chloride | 3895-92-9 | >98.0% | 5MG
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Medchemexpress LLC Ag490 (Tyrphostin AG490) | 133550-30-8 | 99.9% | 200 MG
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AG490 (Tyrphostin AG490) is a small-molecule tyrosine kinase inhibitor that targets JAK2, JAK3, and EGFR, blocking downstream STAT activation. It is supplied for research use and is available as a solid and as DMSO solution for in vitro biochemical and cell-based assays.
- Inhibits JAK2/3 and EGFR-mediated STAT signaling.
- Suitable for in vitro kinase inhibition and cell signaling studies.
- High analytical purity reported at 99.86%.
- Available as a solid and as a DMSO solution for assay preparation.
- CAS number 133550-30-8 supports unambiguous identification.
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Medchemexpress LLC Disuccinimidyl sulfoxide | 1351828-03-9 | MFCD30497419 | 99.8% | 388.35 g·mol⁻¹ | C14H16N2O9S | 100MG
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Disuccinimidyl sulfoxide (DSSO) is a homobifunctional, amine-targeting sulfoxide cross-linker designed for mass-spectrometry-based protein cross-linking and interaction mapping. Its CID-cleavable bonds produce characteristic fragmentation patterns that simplify identification of cross-linked peptides, making it suitable for studies of peptides, proteins, and multisubunit complexes.
- MS-cleavable cross-linker that aids peptide identification
- Homobifunctional, amine-reactive chemistry for lysine targeting
- CID-cleavable sites generate characteristic fragmentation patterns
- Suitable for peptides, proteins, and multisubunit complexes
- Supplied as a crystalline solid for solution preparation
- High purity for analytical mass spectrometry
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000568817 PENDIMETHALIN-200MG
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000568389 SULFACLOZINE-SODIUM-200MG
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Apexbio Technology LLC PF-2545920 1292799-56-4 200mg
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PF-2545920 is a small-molecule inhibitor targeting phosphodiesterase 10A (PDE10A) It is designed to selectively inhibit PDE10A thereby modulating neuronal cAMP and cGMP signaling within cortico-striato-thalamic circuits PF-2545920 exerts its biological activity primarily through selective inhibition of PDE10A In in vitro studies PF-2545920 demonstrates potent inhibitory activity with an IC50 value of 0 37 nM In experimental mouse models it increases striatal cGMP levels at doses around 1 mg/kg Based on these pharmacological properties PF-2545920 holds research potential in the investigation of PDE10A-associated neurobiology and neuropsychiatric conditions such as schizophrenia
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Apexbio Technology LLC Cy5.5 alkyne (non-sulfonated) 25mg
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Cy5 5 alkyne non-sulfonated is a near-infrared fluorescent cyanine derivative equipped with an alkyne functional group for click chemistry applications Through copper-catalyzed azide-alkyne cycloaddition (CuAAC) it forms covalent conjugates with azide-containing biomolecules metabolites or small-molecule ligands Cy5 5 alkyne non-sulfonated is primarily soluble in organic solvents aqueous solutions containing organic co-solvent such as DMSO may be used during conjugation Based on these chemical properties Cy5 5 alkyne non-sulfonated holds research potential in labeling nucleic acids peptides proteins lipids and other biomolecules for biomedical imaging tissue distribution evaluation and related pharmaceutical research applications
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Apexbio Technology LLC WAY-100635 162760-96-5 200mg
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WAY-100635 (CAS 162760-96-5) is a highly selective antagonist of the serotonin 5-HT1A receptor In vitro studies show that WAY-100635 displaces the 5-HT1A radioligand [3H]8-OH-DPAT from rat hippocampal membranes with a pIC50 of 8 87 and acts as a potent antagonist in functional assays without agonist or partial agonist activity In ex vivo guinea pig ileum assays it effectively blocks 5-carboxamidotryptamine-induced 5-HT1A responses (pA2 9 71 at 0 3 nM) In vivo WAY-100635 counteracts 8-OH-DPAT-induced behavioral and thermoregulatory effects in rodents at subcutaneous doses as low as 0 003 0 01 mg/kg It is widely utilized in neuropharmacological research and neuroimaging as a SPECT/PET ligand to investigate 5-HT1A receptor function in psychiatric and neurological disorders
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Apexbio Technology LLC AM-095 free base 1228690-36-5 200mg
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AM-095 free base (CAS 1228690-36-5) is an orally bioavailable antagonist of lysophosphatidic acid receptor 1 (LPA1) It demonstrates inhibitory activity against recombinant human and mouse LPA1 with IC50 values of 0 98 M and 0 73 M respectively In vitro AM-095 suppresses LPA1-mediated chemotaxis in both mouse LPA1/CHO cells (IC50 0 78 M) and human A2058 melanoma cells (IC50 0 23 M) In murine models it blocks LPA-induced histamine release and reduces collagen and protein levels in bronchoalveolar lavage fluid with ED50 values of 8 3 mg/kg and 10 mg/kg respectively Additionally AM-095 decreases macrophage and lymphocyte infiltration in bleomycin-induced lung injury models supporting its utility in studies of LPA1-mediated fibrotic and inflammatory processes
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eMolecules Ethyl 4,6-dichloro-8-iodoquinoline-3-carboxylate | 1929361-06-7 | | 1g
Synthonix - Stock | Ethyl 4,6-dichloro-8-iodoquinoline-3-carboxylate | 1g | 495877839 | E63342 | | 1929361-06-7 | | 396.010 | C12H8Cl2INO2
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PFALTZ & BAUER INC 3 3 -DIETHYLOXATRICARBOC 200MG
NC3835963 3 3 -DIETHYLOXATRICARBOC 200MG
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TARGETMOL CHEMICALS INC TPEN 200MG
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Also available in 1 mL, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. TPEN (TPEDA) is a specific cell-permeable heavy metal chelator. Purity 99.79%
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